Stefan Bassler

Stefan is a Bridging Excellence Postdoctoral Fellow in the Petrov lab at Stanford University and in the Aulehla & Steinmetz labs at EMBL (2025-now). He is fascinated by how evolution can be used to probe the genomic plasticity of biological systems. During his PhD with Nassos Typas at EMBL supported by the Joachim Herz Add-on Fellowship, he mapped the Genomic landscape of resistance evolution by performing high-throughput resistance evolution of the genome-wide KO library in E. coli. He discovered that evolvability genes constrain resistance evolution through gene-gene and gene-gene-drug interactions. In his postdoctoral work, he will assess the inter-kingdom conservation of lifespan variants evolved in yeast.